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Amyloid Precursor Protein (APP) mutation

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Dominantly Inherited Alzheimer Network (DIAN)

Recruiting
  • Alzheimer's Disease
    • Jacksonville, Florida
    • +22 more
    Feb 9, 2022

    Alzheimers Disease, Dementia, Alzheimers Disease, Familial Trial in Worldwide (Gantenerumab, Matching Placebo (Gantenerumab))

    Suspended
    • Alzheimers Disease
    • +2 more
    • Birmingham, Alabama
    • +34 more
    Jan 10, 2023

    Alzheimer, Familial Alzheimer (FAD) Trial in China

    Recruiting
    • Alzheimer Disease
    • Familial Alzheimer Disease (FAD)
      • Hefei, Anhui, China
      • +64 more
      May 29, 2022

      Cerebral MRI Anomalies in Mutated Transthyretin Amyloidosis

      Completed
      • Transthyretin Amyloidosis
      • No intervention,
      • Nîmes, France
        CHU de Nîmes
      Sep 1, 2022

      The Regional Scintigraphic DPD Uptake in Cardiac Transthyretin

      Recruiting
      • Transthyretin Amyloidosis
      • 99mTc-DPD scintigraphy
      • Collection of blood samples and echocardiography
      • Krakow, Lesser Poland, Poland
        Department of Cardiac and Vascular Diseases, John Paul II Hospit
      Apr 14, 2023

      Early-Onset Alzheimer Trial in Aurora, Amsterdam (ALN-APP, Placebo)

      Recruiting
      • Early-Onset Alzheimer Disease
      • Indianapolis, Indiana
      • +5 more
      Jan 19, 2023

      Lumbar Spine Stenosis Specimens for Identification of

      Not yet recruiting
      • Lumbar Spinal Stenosis
      • +5 more
      • Tc99-PYP or Tc99-HDMP Scan
      • Beverly Hills, California
      • +5 more
      Sep 12, 2023

      Alzheimers Disease, Dementia, Alzheimers Disease, Familial Trial in Worldwide (Gantenerumab, Solanezumab, Matching Placebo

      Completed
      Has Results
      • Alzheimers Disease
      • +2 more
      • Birmingham, Alabama
      • +24 more
      Aug 25, 2022

      Metabolic Diseases, Aging Problems Trial in Kelowna (Fed, Fasted)

      Not yet recruiting
      • Metabolic Diseases
      • Aging Problems
      • Fed
      • Fasted
      • Kelowna, British Columbia, Canada
        University of British Columbia - Okanagan Campus
      Aug 22, 2023

      Heart Failure With Preserved Ejection Fraction, Amyloidosis Cardiac Trial in Taipei (NA, observational study)

      Recruiting
      • Heart Failure With Preserved Ejection Fraction
      • Amyloidosis Cardiac
      • NA, observational study
      • Taipei, Taiwan
        National Taiwan University Hospital
      May 8, 2022

      Cholinergic Integrity in Down Syndrome in Association With

      Recruiting
      • Down Syndrome
      • +2 more
      • [18F]-FEOBV Radiotracer
      • Nashville, Tennessee
        Vanderbilt University Medical Center Clinical Research Center
      Jan 31, 2023

      Alzheimers Disease, Dementia, Alzheimers Disease, Familial Trial in Worldwide (Gantenerumab, Solanezumab, Matching Placebo

      Recruiting
      • Alzheimers Disease
      • +2 more
      • Birmingham, Alabama
      • +38 more
      Nov 1, 2021

      STXBP1 Encephalopathy With Epilepsy, SLC6A1 Neurodevelopmental Disorder Trial in Aurora, New York (Glycerol Phenylbutyrate 1100

      Active, not recruiting
      • STXBP1 Encephalopathy With Epilepsy, SLC6A1 Neurodevelopmental Disorder
      • Glycerol Phenylbutyrate 1100 MG/ML [Ravicti]
      • Aurora, Colorado
      • +1 more
      Jan 24, 2023

      Hypertensive Disorder of Pregnancy, Preeclampsia, Gestational Hypertension Trial in Oslo (Access to MumCare app)

      Not yet recruiting
      • Hypertensive Disorder of Pregnancy
      • +3 more
      • Access to MumCare app
      • Oslo, Norway
        Oslo University Hospital
      Apr 18, 2023

      Hypertension Trial in Dallas (Standard Care, Intensive Treatment)

      Active, not recruiting
      • Hypertension
      • Standard Care
      • Intensive Treatment
      • Dallas, Texas
        UT Southwestern Medical Center
      Aug 11, 2022

      Advanced Malignant Solid Tumor, Advanced Ovarian Carcinoma, Metastatic Malignant Solid Tumor Trial (BET Bromodomain Inhibitor

      Recruiting
      • Advanced Malignant Solid Neoplasm
      • +7 more
      • Atlanta, Georgia
      • +2 more
      Nov 3, 2022

      Learn About Tafamidis in Transthyretin Amyloid Cardiomyopathy in

      Not yet recruiting
      • Transthyretin Amyloid Cardiomyopathy
      • (no location specified)
      Oct 11, 2023

      Cognition Disorders Trial in Worldwide (Placebo, Solanezumab)

      Active, not recruiting
      • Cognition Disorders
      • Birmingham, Alabama
      • +67 more
      Jan 17, 2023

      Diabetic Pancreatic Amyloid Deposition on Cognitive Dysfunction

      Recruiting
      • AD
      • +2 more
        • Shanghai, China
          Huashan Hospital
        May 8, 2022

        PET Measures of CSF Clearance in Preclinical Alzheimer's Disease

        Completed
        • Mild Cognitive Impairment
          • New York, New York
            Weill Cornell Medicine
          Oct 18, 2022

          Cognitively Normal Older Adults, Hypertension, Subjective Cognitive Decline Trial in Dallas (Angiotensin II Receptor Blockers

          Recruiting
          • Cognitively Normal Older Adults
          • +3 more
          • Angiotensin II Receptor Blockers (ARBs, losartan) and Calcium Channel Blockers (CCB, amlodipine)
          • PCP
          • Dallas, Texas
            University of Texas Southwestern Medical Center
          Dec 1, 2022

          Systemic Amyloidosis Trial in Knoxville (124I-p5+14 Injection)

          Completed
          • Systemic Amyloidosis
          • 124I-p5+14 Injection
          • Knoxville, Tennessee
            University of Tennessee Medical Center
          Mar 23, 2022

          Depressive Disorder Trial in Tanta (Fluoxetine 20 mg, Dapagliflozin 10mg Tab, Atorvastatin 80mg)

          Not yet recruiting
          • Depressive Disorder
          • Fluoxetine 20 mg
          • +2 more
          • Tanta, Shebeen El-Kom, Egypt
            Faculty of Medicine, Menoufia University
          Mar 19, 2023

          Parkinson, Parkinson Disease Trial in Groningen (Ambroxol Hydrochloride, Placebo)

          Recruiting
          • Parkinson
          • Parkinson Disease
          • Ambroxol Hydrochloride
          • Placebo
          • Groningen, Netherlands
            University Medical Center Groningen
          Apr 13, 2023

          Cognitive Impairment and Affective Mood Disorders in IBD

          Recruiting
          • Inflammatory Bowel Diseases
          • +5 more
          • Cognitive testing
          • Cluj-Napoca, Cluj, Romania
          • +2 more
          Mar 6, 2023